The protein sequences must past three vigorous tests in order to be considered as good candidates to be tested for JCSG. A protein sequence is just a string of proteins that serve a specific function for the entire body.
The selected proteins must pass three filters. The first filter checks for the proper size. If the size of the protein falls within 7 to 80 kDa, the protein is passed on to the next filter, which checks for certain sequences. If the protein fits the proper sequence, it must pass the Protein Data Bank (PDB) Purge, which searches for already known proteins, thus reducing redundancy and time by not testing the same structures again and again. If the protein is unknown to the data bank, it has passed all three filters and is a protein that JCSG researches. If the protein failed any of these three test, it is automatically thrown out of testing. For more information about the tests, click here.
|
Back to the List of Important Definitions
|