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TM0021

  • Deposition Date: 2003/08/01
  • Description: PII like protein glnB
  • Solution Method: X-RAY
  • Start: 1 End: 102 Sequence Type: Complete
  • Fold Function: PII like protein
  • Fold Summary: Class: alpha + beta. Ferredoxin-like fold. Alpha+beta fold with antiparallel beta-sheet. TM0021 forms a thight trimer with an inner channel, constructed by the orthogonal packing of its b-sheets around the crystallographic three-fold.
  • Fold Description: The first structural template for Pfam domain PF02641 and COG domain COG1993. Structural homology to the PII protein (glnB) from E. coli, suggests that TM0021 functions as a signal transduction protein involved in the regulation of the nitrogen signaling cascade. TM0403, a distant homologue of TM0021 in Thermotoga maritima most likely serves in the same pathway as glnK.
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