PSCA Target Info

TM0027;TM0027	Protein Sequence Comparative Analysis (PSCA)

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TM0027 TM0027 JCSG 281908 Protein Purification 04-JUL-20

Protein Sequence Information

TOPSAN

JCSG Internal annotations

ACCESSION	TM0027
DESCRIPTION	Oligopeptide ABC transporter, ATP-binding protein.
ORGANISM	Thermotoga maritima
COMMENT

DR	UNIPROT; Q9WXN4_THEMA
DR	SPTR; Q9WXN4 (flat text); Q9WXN4 (good view)
DR	GenBank; AAD35121
DR	Pfam; PF00005; ABC_tran;
DR	Interpro; IPR003593; AAA_ATPase;
DR	Interpro; IPR003439; ABC_transporter;
DR	PDB; 2YYZ; Highly similar; 06-NOV-07; SUGAR ABC TRANSPORTER, ATP-BINDING PROTEIN;
DR	PDB; 2IT1; Highly similar; 30-OCT-07; 362AA LONG HYPOTHETICAL MALTOSE/MALTODEXTRIN TRANSPORT ATP-B;
DR	FFAS; 281908; Fold and function assignment.
DR	TVPC; TM0027; Homologs in PDB, JCSG and SG center.
DR	OVP; TM0027; Ortholog view popup.
DR	TPM; TM0027; Target PDB monitor.
DR	FSS; TM0027; Target function coverage.

PROPERTY

Residues: 268 aa
Molecule Weight: 30619.07 Dalton
Isoelectric Point: 9.07
Extinction Coefficient: 28420
Gravy Index: -.22
Number of Met residues: 5
Percentage of Met residues: 1.87 %
Number of Cys residues: 1
Percentage of Cys residues: 0.37 %

SEQUENCE  amino acids 268 aa
>TM0027  TM0027 oligopeptide ABC transporter, ATP-binding protein
MSRLVVKNLTKIFSLGFFSKRRIEAVKNVSFEVKEKEIVSLVGESGSGKTTTAKMILRLL
PPTSGEIYFEGKDIWKDIKDRESLVEFRRKVHAVFQDPFASYNPFYPVERTLWQAISLLE
NKPSNKKEALELIKESLFRVGIDPKDVLGKYPHQISGGQKQRIMIARCWILRPLLIVADE
PTSMIDASSRGGIIKLLEELREEQGTSIIFITHDLGLAYYVSDNIFVMKNGEIVERGHPD
KVVLEPTHEYTKLLVGSIPKLYRKLEDL

CDS  cDNA 804 bp
   1 atgagcaggc tcgtcgtgaa gaaccttaca aagatcttct cacttggatt cttctccaag    60
  61 cgtcgtatag aggcggtgaa gaatgtttct tttgaggtga aggagaaaga aatcgtttca   120
 121 ctcgttggag aaagcggttc cggaaaaaca accaccgcaa agatgatact gaggctcctt   180
 181 ccccctacct ccggtgaaat ctactttgaa ggtaaagata tctggaaaga tataaaggac   240
 241 agggaatctc tggttgaatt cagaaggaag gtccacgcgg ttttccagga tccttttgcg   300
 301 agttacaatc ccttctatcc agtcgagaga actctctggc aggccataag tcttctcgag   360
 361 aacaagcctt caaacaagaa agaagcgctc gaactcataa aggagtcact tttcagagtg   420
 421 ggaatagatc caaaggatgt acttggaaag tacccgcacc agatttctgg tggacagaaa   480
 481 caaagaatca tgatagcaag atgctggatc ttgaggcctc ttttgatcgt agcggacgaa   540
 541 cccacatcca tgatagacgc ttcctccaga ggaggtatca taaaactcct cgaagagctc   600
 601 agagaggaac aaggaacgtc catcatattc atcacacacg atctggggct tgcctattac   660
 661 gtttccgaca acattttcgt tatgaagaac ggtgaaatcg tggaaagggg acacccagac   720
 721 aaagtggttc tcgagccgac ccacgaatac accaagctcc tcgtcggtag catcccgaag   780
 781 ctttacagga aactggagga tctg   804

Target constructs
Download sequence in PIR or FASTA format
Chemical properties of sequence with tag

GENE PREDICTION

LEFT END	RIGHT END	FRAME	PREDICTOR	SCORE
25755	26561	-3	Glimmer3 score	14.48	good
			Genemark probabilities	.91 .78	good
			GenemarkHMM class	1	good

Notes

The start codon is a ATG/Methionine in most of sequences, but the GTG/V, TTG/L, CTG/I can be the start codons in some cases as expressing in E.coli. The start codon warning is labelled by RED color in sequence(sample: 10174951).

Protein sequence information contains the annotation contents from both of JCSG and SWISS-PROT. The SWISS-PROT/TrEMBL annotation is accessed from SWALL(SPTR) on the EBI SRS server. PDB homologes show both identical and highly similar proteins with released date and protein function.

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