PSCA Target Info

TM0028;TM0028	Protein Sequence Comparative Analysis (PSCA)

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TM0028 TM0028 JCSG 281909 Crystal Hit 01-AUG-29

Protein Sequence Information

TOPSAN

JCSG Internal annotations

ACCESSION	TM0028
DESCRIPTION	Oligopeptide ABC transporter, ATP-binding protein.
ORGANISM	Thermotoga maritima
COMMENT

DR	UNIPROT; Q9WXN5_THEMA
DR	SPTR; Q9WXN5 (flat text); Q9WXN5 (good view)
DR	GenBank; AAD35122
DR	Pfam; PF00005; ABC_tran;
DR	Pfam; PF08352; oligo_HPY;
DR	Interpro; IPR003593; AAA_ATPase;
DR	Interpro; IPR003439; ABC_transporter;
DR	PDB; 4FWI; Highly similar; 30-JAN-13; ABC-TYPE DIPEPTIDE/OLIGOPEPTIDE/NICKEL TRANSPORT ATPASE COMP;
DR	FFAS; 281909; Fold and function assignment.
DR	TVPC; TM0028; Homologs in PDB, JCSG and SG center.
DR	OVP; TM0028; Ortholog view popup.
DR	TPM; TM0028; Target PDB monitor.
DR	FSS; TM0028; Target function coverage.

PROPERTY

Residues: 330 aa
Molecule Weight: 37302.96 Dalton
Isoelectric Point: 8.17
Extinction Coefficient: 26930
Gravy Index: -.07
Number of Met residues: 14
Percentage of Met residues: 4.24 %
Number of Cys residues: 5
Percentage of Cys residues: 1.52 %

SEQUENCE  amino acids 330 aa
>TM0028  TM0028 oligopeptide ABC transporter, ATP-binding protein
MKEILLKAENVRAYYKLEKVSVKAVDGLSFEILEDEVIGVVGESGCGKTTLSNVIFMNMV
KPLTLVDGKIFLRVNGEFVELSSMTRDEVKRKFWGKEITIIPQAAMNALMPTIRMEKYVR
HLAESHGIDEEELLDKARRRFEEVGLDPLWIKRYPFELSGGMRQRAVIAIATILNPSLLI
ADEPTSALDVVNQKVLLKVLMQMKRQGIVKSIIFITHDIATVRQIADRMIIMYAGKIVEF
APVESLLEKPLHPYTQGLFNSVLTPEPEVKKRGITTIPGAPPNLINPPSGCRFHPRCPHA
MDVCKEKEPPLTEIEPGRRVACWLYMEERA

CDS  cDNA 990 bp
   1 atgaaagaaa tacttttgaa agcagaaaat gtgagggcct actataaact ggaaaaggtt    60
  61 tctgtcaaag ctgtggatgg tttgtctttt gaaatactgg aagacgaagt tataggggtt   120
 121 gtcggtgaat ctggttgtgg aaagacaact ctctcgaacg tgatcttcat gaacatggta   180
 181 aagccgttga cactcgttga tggaaagata tttctgagag ttaacggaga gtttgtggag   240
 241 ctgtcgtcca tgacaagaga cgaagtgaaa agaaaattct ggggaaaaga gataacgata   300
 301 ataccccagg cagcgatgaa cgcactgatg cccaccatca ggatggaaaa gtatgtgagg   360
 361 catcttgcgg aatcgcacgg aatagacgaa gaggaacttt tggataaagc cagaagaaga   420
 421 tttgaagagg tagggctcga tccactttgg attaaaaggt atccttttga actaagtggt   480
 481 ggaatgagac aaagagccgt gatagcgatc gcaactatat tgaatccgag ccttctcata   540
 541 gctgatgagc caacttccgc tctggatgtt gtgaatcaaa aggttctttt gaaagtcctg   600
 601 atgcagatga aacgccaagg aatcgtgaag agcataatct tcatcaccca tgacatagcg   660
 661 actgtaaggc agatcgcaga cagaatgatc atcatgtacg ctggaaagat agttgagttc   720
 721 gcacctgtgg aaagtctcct ggaaaaaccg cttcatcctt acacccaggg gcttttcaat   780
 781 tcggttctca ctccagaacc agaggtgaaa aagagaggaa tcaccaccat tcctggagct   840
 841 ccacccaatc tcataaatcc tccatctggc tgcagattcc atcctagatg ccctcacgcg   900
 901 atggatgtct gtaaagaaaa agaaccaccg ctaacggaga tagaaccagg aagaagagtt   960
 961 gcatgctggc tttacatgga ggagagagca   990

Target constructs
Download sequence in PIR or FASTA format
Chemical properties of sequence with tag

GENE PREDICTION

LEFT END	RIGHT END	FRAME	PREDICTOR	SCORE
26558	27550	-2	Glimmer3 score	12.18	good
			Genemark probabilities	.85 .85	poor
			GenemarkHMM class	1	good

Notes

The start codon is a ATG/Methionine in most of sequences, but the GTG/V, TTG/L, CTG/I can be the start codons in some cases as expressing in E.coli. The start codon warning is labelled by RED color in sequence(sample: 10174951).

Protein sequence information contains the annotation contents from both of JCSG and SWISS-PROT. The SWISS-PROT/TrEMBL annotation is accessed from SWALL(SPTR) on the EBI SRS server. PDB homologes show both identical and highly similar proteins with released date and protein function.

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