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JCSG Scientific Advisory Board (SAB)


 
Overview

JCSG Scientific Advisory Board (SAB) - The Scientific Advisory Board is composed of internationally recognized experts in the fields comprising the scope of the current and planned research. They provide objective reviews of the progress of the project, and make recommendations to the Steering Committee on program issues, and interactions with the PSI:Biology Partnerships and the community. The Steering Committee utilizes the input from the SAB in its annual evaluation of the JCSG and for help in prioritizing goals and milestones for the coming year.
 
Board Members

The scientific advisory Board (SAB) is comprised of the following members:
Sir Tom L. Blundell, FRS, FMedSci - http://www.bioc.cam.ac.uk/uto/blundell.html
University of Cambridge
  Professor Blundell is Director of Research and Professor Emeritus at the University of Cambridge. He is Chair of the Biotechnology and Biological Sciences Research Council (BBSRC). He is a world leader in research on protein structure and function, has pioneered many aspects of the protein structure field, and is an authority on structure-based drug design and protein bioinformatics. In 2009, he completed his terms as Sir William Dunn Professor of Biochemistry, and Head of the School of Biological Sciences, at the University of Cambridge. He is a Member of EMBO and Academia Europaea, and is a Fellow of the Royal Society and of the Academy of Medical Sciences. He has Honorary Fellowships at Linacre and Brasenose Colleges, Oxford, and at Birkbeck College, London, a Professorial Fellowship at Sidney Sussex, Cambridge, and Honorary Doctorates from fifteen universities. He previously held positions in Oxford and Sussex Universities, and the Bernal Chair of Crystallography in Birkbeck College, University of London.

He has consulted with a number of large pharmaceutical companies, including Pfizer, Parke Davis, SKB, Zeneca and Glaxo. He was previously on the Board of Celltech and Chairman of their Science and Technology Committee. He co-founded Astex Therapeutics Ltd., a private drug discovery company. He has also played an active role in UK national science policy in appointments as Director General of the Agricultural and Food Research Council (1991-1994), founding Chief Executive of the BBSRC (1994-1996), Chairman of the Royal Commission on Environmental Pollution (until 2005), and President of the UK Biosciences Federation (until 2008). He is President Elect of the UK Science Council, established by Royal Charter in 2003 with the objects of advancing science and its applications for public benefit.
 
Michael Cooke, Ph.D. - http://www.gnf.org/technology/immunology/
Genomics Institute of the Novartis Research Foundation
  Dr. Cooke is Director of Immunology at the Genomics Institute of the Novartis Research Foundation, in San Diego, California. Dr. Cooke received his Ph.D. in Biochemistry from the University of Washington, Seattle, in 1991, followed by postdoctoral work at Stanford University. From Stanford he went to the hematopoietic stem cell company, SyStemix, Inc., in Palo Alto, CA, where he was Director of Functional Genomics. He joined the Genomics Institute of the Novartis Research Foundation (GNF) in 1999. As Director of Immunology, he is responsible for oversight of immunology research at GNF, leading a team of more than 40 scientists to discover targets and develop therapeutics to treat autoimmunity and to boost vaccines, and serves as a member of the research management team at GNF. His own research includes the application of genomics tools and chemical screens to study the biology of hematopoietic stem cells and the adaptive immune system and the translation of these findings into novel therapeutics to treat immune disorders and improve HSC transplant outcomes.
 
James  Naismith, Ph.D., FRSE - http://www.eastchem.ac.uk/profiles/sta/naismith.html
University of St. Andrews
  Dr. Naismith is Professor of Chemical Biology and Director of the Biomedical Sciences Research Complex, Center for Biomolecular Sciences, at the University of St. Andrews. Dr. Naismith received his Ph. D. in Structural Chemistry from the Victoria University of Manchester as a Carnegie Scholar. He did postdoctoral work at the Howard Hughes Medical Institute at the University of Texas Southwestern Medical Center as a NATO/SERC fellow. Dr. Naismith led the Scottish Structural Proteomics Facility a collaborative high throughput structural genomics project that involved the Universities of St. Andrews, Dundee, Glasgow and Warwick. From 2003-2009, he was Chair of CCP4, the BBSRC-funded Collaborative Computing Project 4, which produces and supports software for macromolecular X-ray crystallography.

Dr. Naismith is a Fellow of the Royal Society of Edinburgh, and his work has been recognized by the award of the Royal Society of Chemistry (RSC) Carbohydrate Prize 2000, BBSRC Career Development Fellowship 2002, Leverhulme Prize in Molecular Biology 2002, the Biochemical Society Colworth Medal 2004, the RSC Corday-Morgan Medal 2004, and the RSC Jeremy Knowles Award 2009. Dr. Naismith was elected to the European Molecular Biology Organization (EMBO) in 2009.
 
Karen Nelson, Ph.D. - http://www.jcvi.org/cms/about/bios/knelson/
J. Craig Venter Institute
  Dr. Nelson is President of the J. Craig Venter Institute (JCVI). She received her undergraduate education from the University of the West Indies, and her Ph.D. in Microbiology from Cornell University in 1997. Dr. Nelson has extensive experience in microbial ecology, genomics and metagenomics as well as in microbial physiology. In 1999, at The Institute for Genomic Research (TIGR), she led the genome sequencing of Thermotoga maritima MSB8, a bacterium isolated in water from a thermal vent off the coast of Italy, and the landmark publication provided insights into microbial evolution. She has also been involved in the analysis of the microbiota of the human stomach and gastrointestinal tract, and Dr. Nelson and her group were part of a national team of researchers who completed the first comprehensive metagenomic survey of the human gastrointestinal tract. Dr. Nelson is also Editor-in-Chief of Microbial Ecology and Advances in Microbial Ecology, and a member of the NRC Committee on Biodefense, the American Society for Microbiology Communications Committee, and is a Fellow of the American Academy of Microbiology.

Dr. Nelson was a key investigator in the multi-center NIH Human Microbiome Project, which focused on understanding the microbes that live in and on the human body and their contribution to human health and disease. She has authored or co-authored over 100 publications.
 
James C. Paulson, Ph.D. - http://www.scripps.edu/research/faculty/paulson
The Scripps Research Institute
  Dr. Paulson is Professor in the Departments of Chemical Physiology and Molecular Biology at The Scripps Research Institute (TSRI), and has been serving as Principal Investigator for the NIGMS-funded Consortium for Functional Glycomics (CFG), an international consortium of over 530 investigators, from 2001-present. He is Co-chair of the Human Glycomics/Proteomics Initiative (HGPI), from 2005 – present. He received his Ph.D. in Biochemistry from the University of Illinois at Champaign-Urbana, and did postdoctoral work at the Duke University Medical Center in Durham, North Carolina. From Duke, he went to the University of California, Los Angeles, School of Medicine, where he advanced to Professor and Vice-Chair of the Department of Biological Chemistry.

Dr. Paulson’s work has been recognized by the Society of Glycobiology Karl Meyer Award 2009, and the Netherland Foundation for Chemical Research Bijvoet Medal 2008. From 1990, he served as Vice President of Research, Chief Scientific Officer and Board Member of Cytel Corporation, a publically traded biopharmaceutical company, until its merger with Epimmune in 1999. Dr. Paulson has served on Scientific Advisory Boards for: Neose Technologies, Inc. (1999-2008), Virdante Pharmaceuticals Inc. (2007-present), Zacharon (2006-2009), Nexbio (2004-present), Alberta Ingenuity Center for Carbohydrate Science-AICCS, (2003-present), Institute for Biological Sciences-IBS, NRC, Ottawa (2004-present) and the Boston University Mass Spectrometry Resource, (2006-present).
 
Joseph Puglisi, Ph.D. http://med.stanford.edu/profiles/Joseph_Puglisi
Stanford University School of Medicine
  Dr. Puglisi is Professor and Chair of the Department of Structural Biology at Stanford University School of Medicine, and Director of the Stanford Magnetic Resonance Laboratory (SMRL) at Stanford University School of Medicine. He received his Ph.D. from the University of California, Berkeley, in Biophysical Chemistry. His research focuses on studying the role of RNA in cellular processes and disease. He is also Director of the International School of Biological Magnetic Resonance, EMFCSC, in Erice, Italy.

Dr. Puglisi was awarded fellowships from the Alfred P. Sloan Research Foundation (1997), and the David and Lucille Packard Fellowship in Science and Engineering (1994-1999). In 1993, he was selected as recipient of the Camile and Henry Dreyfus Teacher-Scholar Award. He currently serves on the Scientific Advisory Boards of the biopharmaceutical companies 3-V Biosciences, Inc., and PTC Therapeutics.
 
James Wells, Ph.D. - http://cancer.ucsf.edu/people/wells_james.php
University of California, San Francisco
  Dr. Wells is Chairman of the Department of Pharmaceutical Chemistry at the University of California, San Francisco (UCSF), and is professor in the UCSF School of Medicine’s Department of Cellular and Molecular Pharmacology. He received his Ph.D. in Biochemistry from Washington State University, where he received a Damon M. Runyon - Walter Winchell Postdoctoral Fellowship 1979-1981, and did further postdoctoral work at the Stanford University Medical School. Dr. Wells is an internationally recognized biochemist and leader in the development of new technologies for engineering proteins and for identifying small molecules to aid in drug discovery. His research spans the multiple disciplines of biophysics, cell biology, molecular biology, biochemistry and chemistry. Dr. Wells founded and directs the Small Molecule Discovery Center (SMDC) at UCSF, which assists researchers in the identification of small molecules that modulate biochemical or cellular processes and have the potential to alter disease states.

Dr. Wells is a member of the National Academy of Sciences. In 2005, he joined UCSF as the first holder of the Harry Wm. and Diana V. Hind Distinguished Professorship in Pharmaceutical Sciences. His work has been recognized by the Perlman Lecture Award of the ACS Biotechnology Division 2006, the Hartwell Individual Biomedical Research Award 2006, the Protein Society Hans Neurath Award 2003, the American Peptide Society Vincent du Vignead Award 1998, the Protein Society Christian B. Anfinsin Award 1998, and the Pfizer Award (given by the American Chemical Society for achievements in enzyme chemistry) 1990. Prior to joining UCSF, Dr. Wells was a founding scientist in Genentech’s Protein Engineering Department. In 1998, he founded Sunesis Pharmaceuticals where he served as President and Chief Scientific Officer. Dr. Wells is a named inventor on more than 50 patents issued or filed.
 
Todd Yeates, Ph.D. - http://people.mbi.ucla.edu/yeates/
University of California, Los Angeles
  Dr. Yeates is Professor in the Department of Chemistry and Biochemistry at the University California, Los Angeles (UCLA). He received his Ph.D. at UCLA, followed by postdoctoral work at The Scripps Research Institute. His interdisciplinary research, combining molecular biology with computing and mathematics, has focused on macromolecular structure and computational genomics.

Dr. Yeates’ UCLA honors include the Hansen-Dow Award for Excellence in Teaching (2004), and the McCoy Award for Excellence in Research (1995). His work was also recognized by the Pittsburgh Diffraction Society Sidhu Award (1993), and he was a National Science Foundation Presidential Young Investigator (1991). Dr. Yeates is a member of the Molecular Biology Institute, the California NanoSystems Institute, the UCLA-DOE Institute of Genomics and Proteomics, and a Fellow of the American Association for the Advancement of Science.
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