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Target ID: 422603
Target Name:WT2001B  Protein Accession:BC013200  Local Accession: WT2001B.LCK  cDNA Accession:BC013200  PSCA PDB:4d8k

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Proposed Target  
 
Active Target  
 
PCR Testing  
 
Amplifer Generation  
 
Orientation  
 
Plasmid Purification  
 
Micro Expression  
 
Expression  
 
Protein Purification  
 
Crystallization  
 
Crystal Hit  
 
SDC Receiving  
 
Screening  
 
Data Collection  
 
Integration  
 
Scaling  
 
Truncating  
 
Phasing  
 
MR Tracing  
 
Refining  
 
QC  
 
Validation  
 
PDB Deposition  
 
Proposed Target
 
Active Target
 
PCR Testing
 
Amplifer Generation
 
Orientation
 
Plasmid Purification
 
Micro Expression
 
Expression
 
Protein Purification
 
Crystallization
 
Crystal Hit
 
SDC Receiving
 
Screening
 
Data Collection
 
Integration
 
Scaling
 
Truncating
 
Phasing
 
MR Tracing
 
Refining
 
QC
 
Validation
 
PDB Deposition
 
 
Status View
 
Chrono View
 
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Name: BC013200 Homo sapiens lymphocyte-specific protein tyrosine kinase, src-Family Kinases are nonreceptor tyrosine kinases that are reported to be critical for cancer progression. Protein kinase has SH2, SH3 and Pkinase_Tyr domains (PF00017 , PF00018, PF07714).  Start Position: 53  End Position: 226
GNF Target Alias: HK100:SpeedET-WT2001B-hum-539-53-226  Sequence Type: SEGMENT  Residues: 174
DNA Length: 522  Molecular Weight: 19505.64  Isoelectric Point: 5.86
Epsilon 280: 22460  Gravy Index: -0.60  Species: H. sapiens
Activated: 4  Alanine Absolute: 9  Alanine Relative: 0.0517
Arginine Absolute: 10  Arginine Relative: 0.0575  Asparagine Absolute: 10
Asparagine Relative: 0.0575  Aspartic Acid Absolute: 8  Aspartic Acid Relative: 0.0460
Cysteine Absolute: 2  Cysteine Relative: 0.0115  Glutamic Acid Absolute: 13
Glutamic Acid Relative: 0.0747  Glutamine Absolute: 9  Glutamine Relative: 0.0517
Glycine Absolute: 15  Glycine Relative: 0.0862  Histidine Absolute: 6
Histidine Relative: 0.0345  Isoleucine Absolute: 7  Isoleucine Relative: 0.0402
Leucine Absolute: 18  Leucine Relative: 0.1034  Lysine Absolute: 7
Lysine Relative: 0.0402  Methionine Absolute: 0  Methionine Relative: 0.0000
Phenylalanine Absolute: 11  Phenylalanine Relative: 0.0632  Proline Absolute: 11
Proline Relative: 0.0632  Serine Absolute: 17  Serine Relative: 0.0977
Threonine Absolute: 8  Threonine Relative: 0.0460  Tryptophan Absolute: 3
Tryptophan Relative: 0.0172  Tyrosine Absolute: 4  Tyrosine Relative: 0.0230
Valine Absolute: 6  Valine Relative: 0.0345  Project: Williamson and Salomon center, set 2
Selection Date: 2010-11-11  
ProposalRelationshipOwnerLab Name
95PSI Biological PartnerWilliamson and SalomonPartnership for T-Cell Biology

STAGE: Proposed Target

STAGE: Active Target

STAGE: PCR Testing

STAGE: Amplifer Generation

STAGE: Orientation

STAGE: Plasmid Purification

STAGE: Micro Expression

STAGE: Expression

STAGE: Protein Purification

STAGE: Crystallization

STAGE: Crystal Hit

STAGE: SDC Receiving

STAGE: Screening

STAGE: Data Collection

STAGE: Integration

STAGE: Scaling

STAGE: Truncating

STAGE: Phasing

STAGE: MR Tracing

STAGE: Refining

STAGE: QC

STAGE: Validation

STAGE: PDB Deposition
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